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Three college friends go to the biggest party of the year, each looking for something different: love, sex and a simple human connection. When a supernatural phenomenon disrupts the party, it lights a fuse on what will become the strangest night anyone has ever seen. As the three friends struggle to find what they’re looking for, the party quickly descends into a chaos that challenges if they can stay friends or if they can even stay alive.
In London, after investigating crack addicted junkies for an article in her newspaper, Amy Klein watches a bizarre videotape where an underground group of youngsters in Bucharest apparently becoming zombies. Amy finds Marla dead with a puzzle cube in her hands. She brings the object to her hotel room, and opens it, beginning her journey to hell.
Angela, the universe’s most unpleasant party crasher, returns! Angela’s sister, Mouse, is taken by her bullying Catholic school classmates to a party at Angela’s favorite haunt, and before long, everybody’s being turned into demons and only a butt-kickin’ nun, who wields her ruler like a mighty sword of steel, can save the day.
When a local woman disappears and the police can’t seem to find any leads, her father turns to a poor young woman with psychic powers. Slowly she starts having visions of the woman chained and in a pond. Her visions lead to the body and the arrest of an abusive husband, but did he really do it?